Fear of the LORD is the foundation of true knowledge, but fools despise wisdom and discipline (Proverbs 1:7).
The book of Proverbs starts out with a purpose statement. Chapter one versus two, three, and four, describe who will benefit the most from studying the proverbs. Solomon tells us about the kind of attitude that will receive the most impactful result from the wisdom of God. This attitude is called “fear of the Lord.” The fear that Solomon is talking about is a humble, high respect, and attentive position toward God. The result of this fear will make us ready to benefit from God’s wisdom. The word fear means an attitude of awe and respect, a holy reverence. Without this attitude we will probably not be in a proper position to receive what God tells us.
the rest of this verse tells us, people who do not have this awe and respect of God end up despising His wisdom. But people who make it a habit to highly respect or have reverence for God and practice His wisdom, will find that life makes sense. Then we seem to work in accordance with the way God designed our life. As you follow wisdom, you get the most out of life!